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It prohibits specific formulations, marketing claims, and delivery methods that cross from supplement territory into unapproved drug territory

Despite the promising therapeutic potential of azelaic acid in melasma, however due to limited water solubility and poor skin permeability, its conventional topical formulations have been fabricated in higher doses (10%20%) to achieve the desired clinical outcome (Sieber and Hegel, 2014

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Evidence-based treatments for depression, including cognitive behavioural therapy (CBT), antidepressants, and other psychological interventions, remain the first-line approaches recommended by NICE for managing depressive disorders

They are primarily captured under codes for organo-sulfur compounds, food preparations, medicaments, and cosmetic/toilet preparations